WASHINGTON (AP) — President Donald Trump declared Tuesday it's time to "let Obamacare fail" after the latest GOP health care plan crashed and burned in the Senate, a stunning failure for the president, Republican leader Mitch McConnell and a party that has vowed for years to abolish the law.

In a head-spinning series of developments, rank-and-file Republican senators turned on McConnell and Trump for the third time in a row, denying the votes to move forward with a plan for a straight-up repeal of "Obamacare." This time, it was three GOP women — Susan Collins of Maine, Lisa Murkowski of Alaska, and Shelley Moore Capito of West Virginia — who delivered the death blow.

All had been shut out of McConnell's initial all-male working group on health care.

McConnell, who could afford to lose only two votes in the narrowly divided Senate, had turned to the repeal-only bill after his earlier repeal-and-replace measure was rejected on Monday. That had followed the failure of an earlier version of the bill last month.

The successive defeats made clear that despite seven years of promises to repeal former President Barack Obama's Affordable Care Act, Republicans apparently cannot deliver. Nonetheless, McConnell insisted he would move forward with a vote on his measure to repeal the law, effective in two years, with a promise to work — along with Democrats — to replace it in the meantime.

The vote could come as soon as Wednesday. It appears doomed to fail, but GOP leaders want to put lawmakers on record on the issue and move on.

At the White House, Trump appeared to recognize defeat, at least for the moment, while insisting he bore none of the blame.

"I think we're probably in that position where we'll just let Obamacare fail," the president said. "We're not going to own it. I'm not going to own it. I can tell you that the Republicans are not going to own it. We'll let Obamacare fail and then the Democrats are going to come to us and they're going to say, 'How do we fix it?'"

Despite the current law's problems, most health care experts do not believe it is at immediate risk of outright failure, and Democratic cooperation to adjust the law is far from assured.

Nor does it appear likely that Republicans can escape owning the problems with the law and the health care system overall, now that they control the House, Senate and White House, partly on the strength of campaigning against the law.

"They seem to have this notion that they can be a majority party, and have control of the White House, and not be responsible for bringing down the health care system," said Democratic Sen. Dick Durbin of Illinois. "It doesn't work that way."

Asked how he would justify the GOP's failure on health care to voters, McConnell responded: "Well, we have a new Supreme Court justice" — suggesting inaction on health care would be forgiven because of that success along with some regulatory roll-backs.

As the day began Tuesday, McConnell was hunting for votes to open debate on a revived version of legislation Congress sent to Obama's desk in 2015 that would have repealed major portions of Obamacare, with a two-year delay built in. He had turned to that approach after getting stunned Monday night by defections by Sens. Mike Lee of Utah and Jerry Moran of Kansas on a repeal-and-replace bill.

Many Republicans support the repeal-only approach, and they question how senators who voted for the legislation two years ago could oppose it now.

"Were going to find out if there's hypocrisy in the United States Senate in the next few days I'm afraid," said Sen. David Perdue, R-Georgia.

But for others, the implications were too severe now that the bill could actually become law with a Republican president in the White House ready to sign it. The Congressional Budget Office has estimated that more than 30 million people would lose insurance over a decade under the legislation.

Collins voted against the legislation in 2015 while Murkowski and Capito both supported it. Murkowski told reporters Tuesday that repealing the Affordable Care Act without the promise of a replacement would cause uncertainty and chaos.

"To just say repeal and 'Trust us, we're going to fix it in a couple of years,' that's not going to provide comfort to the anxiety that a lot of Alaskan families are feeling right now," she said.

Said Capito: "I did not come to Washington to hurt people."

What's next? Go back to the committee room and work on a bipartisan basis "in a way that the public feels that we are really working toward their best interests, Murkowski said. "It's where we should have started. ... And yes, this is hard."

Alaska has extremely high medical costs because many residents live in remote areas, and it also benefits from Obama's expansion of Medicaid coverage. Murkowski has been wary of anything that would jeopardize federal funds for her state.

Similar to legislation the House approved in May after its own setbacks, McConnell's repeal-and-replace bill would have canceled Obama's tax penalties on people who don't buy coverage and cut the Medicaid program for the poor, elderly and nursing home residents. It would have rolled back many of the statute's requirements for the policies insurers can sell and eliminate many tax increases that raised money for Obama's expansion to 20 million more people, though it retained the law's tax boosts on high earners.

More than 20 million people would have lost insurance coverage under the McConnell plan, according to the Congressional Budget Office — compared to more than 30 million under the repeal-only version rejected Tuesday.