LONDON (AP) — The makers of Budweiser aren't satisfied with being the kings of beer. They want an empire.

Anheuser-Busch InBev, the world's biggest brewing company and the owner of Budweiser, announced Wednesday it wants to buy SABMiller, the second-largest brewer — and the maker of long-time rival brand Miller Genuine Draft.

The deal would create a multinational behemoth valued at around $275 billion with annual sales of $73.3 billion, more than three times its closest rival, Heineken.

AB InBev already claims six of the world's most valuable beer brands, which besides Budweiser include Corona, Stella Artois and Beck's. Taking over Miller in the U.S. would likely draw objections from regulators worried the deal might stifle competition and lead to higher prices for consumers.

But whereas a lot of the attention will focus on the best-known brands in the U.S. and Europe, AB InBev's sights are on other countries. As profits wane in the Americas, AB InBev wants to expand into Africa.

Enticingly, SABMiller has a huge presence in Africa, the next beer frontier.

"The days of big profits in the U.S. are gone," said Jonny Forsyth, a global drinks analyst for Mintel, the market research firm. "They have to position themselves in the big beer growth market for the next 10 years."

Shares of SABMiller rocketed about 20 percent higher on news of the approach, pushing its market value to around $90 billion. Shares of AB InBev rose 6 percent.

The companies are being pushed into consolidation by eroding market share and competition, ironically, by the little guy. Craft beers now make up 11 percent in volume in the U.S. market, Mintel said.

AB InBev and SABMiller are themselves products of this consolidation trend. In every way, they are thinking big.

"We are driven by our passion to create a company that can stand the test of time and create value for our shareholders, not only for the next 10 or 20 years but for the next 100 years," Anheuser-Busch InBev CEO Carlos Brito and chairman Kees J. Storm wrote in a letter to shareholders. "Our mindset is truly long term."

But Africa, where home brew still dominates, offers a chance to grow. And that's where SABMiller— the one-time South African industrial conglomerate — offers a foothold.

The former South African Breweries expanded in the early 1990s when Nelson Mandela's release from prison led to a lifting of sanctions on South Africa and allowed the company to expand abroad.

Though the European beer market was dominated by the likes of Guinness and Heineken, SAB took advantage of the opening offered by the fall of the Berlin Wall to sweep into Eastern Europe and buy brewers on the cheap. Its expansion also stretched to other African countries including Mozambique, and to Asia.

The company bought Czech brewer Plzensky Prazdroj, maker of Pilsner Urquell, in 1999, U.S.-based Miller Brewing Co. in 2002 and Foster's of Australia in 2011. Today the company employs about 69,000 people in more than 80 countries, from Australia to Zambia, Colombia and the Czech Republic.

AB InBev is likewise the product of many mergers. Its current form emerged from a 2008 takeover of U.S. icon Anheuser Busch Cos. by Brazilian-Belgian brewer InBev. The company has operations in 25 countries and makes more than 200 beers.

SABMiller, now based in London, said Wednesday that it "will review and respond as appropriate to any proposal which might be made."

If the deal were to happen, it would create a company with 31 percent of the global beer market, said Harry Schuhmacher, editor of Beer Business Daily, a trade publication. That would dwarf the next biggest player, Heineken, which has 9 percent of the global market.

Under U.K. takeover rules, AB InBev has until 5 p.m. on Oct. 14 to make an offer for SABMiller or walk away.

SABMiller sold 324 million hectoliters (8.56 billion gallons) of lager, soft drinks and other alcoholic beverages in the year ended March 31. AB InBev sold 459 million hectoliters.

In the case of a deal, the sheer size of the combined company is expected to push regulators to require the sale of some brands to ensure fair competition. That could be the case for Miller in the U.S.

"Anytime you have the No. 1 and No. 2 merging, it's going to be looked at closely," said Erik Gordon, a professor at the University of Michigan's Ross School of Business who studies antitrust issues.